DHA 

Docosahexaenoic Acid (DHA)

What Is DHA?

DHA is a type of polyunsaturated omega-3 fatty acid or in short, PUFA.

It is a key component of every cell in the human body; and is highly concentrated in the brain and eyes. DHA, being a PUFA is susceptible to oxidation, particularly in the brain which is a highly metabolically active tissue. Nature protects DHA in the brain by packing it with potent antioxidants, like lutein and Natural Vitamin E (NVE).1

At times, especially during periods of rapid growth, the human body has limited ability to produce sufficient DHA. Hence, diet can be the main source of DHA for most individuals.

Benefits of DHA

Vital Component In Cell Development

Essential For Brain & Eye Development

Supports Cognitive Function

Influences Learning Ability

DHA is a key nutrient that is vital for overall growth and development, particularly for brain and eye development, especially during the formative years of children.

When it comes to brain and eye development, DHA is one of the most widely recognised nutrients.  Sufficient DHA intake is believed to be important for the normal growth and maturation of the brain and eyes.

DHA also supports cognitive development. Studies at various life stages indicate that DHA supports normal IQ2 and preserves visuo-spatial learning and memory3. For the brain, adequate DHA allows for optimal function.

Daily Recommended Intake of DHA

During pregnancy, mums provide DHA to the foetus. Pregnant and lactating woman are advised to achieve an average daily intake of minimally 200mg of DHA4, which will serve as building blocks of the growing foetus’s brain.

The recommended intakes of DHA for children are:

  • ~10-12 mg/kg body weight for 13-24 months
  • ~100 mg/day for 2-4 years
  • ~130 mg/day for 4-6 years
  • ~160 mg/day for 6-10 years.5

Sources of DHA

While the body can convert the essential long chain polyunsaturated fat, alpha-linolenic acid to DHA, some experts believe that during the period of rapid growth, this may not provide enough and, therefore, recommend ensuring adequate DHA in the diet. Listed below are some food sources of DHA.

Seafood

  • Herring
  • Trout
  • Mackerel
  • Salmon
  • Anchovies
  • Sardine
  • Tuna
  • Microalgae

DHA Fortified Food

  • Milk
  • Eggs
  • Juice

Oil

  • Fish Oil
  • Algal Oil

 

Signs And Consequences Of Deficiency

As DHA is an important nutrient for the human’s body, the lack of DHA may impact optimal development and long-term health.

Brain Development6

Vision7

Heart Health8

In the growing years of kids, DHA supports brain tissue growth, and the deficiency of DHA may have negative impacts on brain development and function.

DHA also helps activate rhodopsin, a membrane protein in the rods of the eyes. As rhodopsin helps the brain receive images, DHA deficiency may impair vision.

In adults, low levels of DHA are associated with increased risk of heart disease and death. Some experts believe that DHA supplements can improve multiple risk factors of heart diseases including blood pressure, cholesterol, and triglycerides.

Did You Know?

DHA helps with certain learning outcomes, visual acuity and brain development.

References:

1,2: 1. Leung HH et al. Neurochem Res. 2020 May;45(5):1007-1019. 2. Kuchan et al. Br J Nutr. 2016 Jul;116(1):126-31.
2 Cohen J.T, et al. Am. J. Prev. Med. 2005; 29:366–374.
3 Yurko-Mauro K. Alzheimers Dement. 2010;6:456–464.
4 Koletzko B et al. J Perinat Med. 2008;36(1):5-14.
5 Food and Agriculture Organization of the United Nations . Fats and fatty acids in human nutrition report of an expert consultation, November 10-14, 2008. Geneva: FAO Food and Nutrition Paper 91. Rome; 2010. http://www.fao.org/docrep/013/i1953e/i1953e00.pdf (accessed September 23, 2022)
DiNicolantonio JJ. Nutrients. 2020 Aug 4;12(8):2333.
Shindou H et al. J Biol Chem. 2017 Jul 21;292(29):12054-12064.
Ginter E et al. Bratisl Lek Listy. 2010;111(12):680-5.

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